How Carnitine Affects Weight Loss

Carnitine - Healthcodes DNA™

Carnitine as a weight loss supplement 

Before discussing carnitine for weight loss, we must first examine the disease of weight gain. Obesity is a severe health problem due to the higher price of health issues around the globe. With fat loss, it’s becoming hard in just this modern world; weight reduction is gaining so much focus. Anti-obesity narcotics had no adverse reactions to obtrusive cosmetic procedures, so they are more often utilized than in other alternatives like vigorous exercise. The mitochondrial enzyme has so far adhered to mitigating cardiovascular events, end-stage bladder diseases, dialysis-related heart problems, diagnosis of persistent depression, and recovery of non-alcoholic liver failure. Carnitine is one of the solutions to this growing issue as it burns the excess fats from our bodies. Its use as a weight-loss supplement was initiated in this century. 

In this article, we will discuss why we need carnitine? Does it work for weight loss? Does it work for the fat burn? Is it correct up to all the hype that is out there? Metabolism and function of carnitine and its metabolism related to weight loss in humans and the availability of different supplements we use for weight loss. At the same time, we will also look at various other functions related to carnitine. 

History of Carnitine

In 1905, carnitine was first discovered in meat extract. In 1927, the correct structure for carnitine was proposed. Next, in 1948, a new vitamin, BT, was found essential for the growth of the yellow mealworm. The T derives from the Latin name of this species, Tenebrio Molitor. Afterward, this Vitamin identifies as carnitine.  After that discovery of this enzyme acetyltransferase (CRAT) takes place. And finally, in 1958, I.B. Fritz discovered that it stimulates long-chain fatty acid oxidation in mitochondria.

 

Carnitine - Healthcodes DNA™

Meaning of Carnitine

This word comes from the Latin carnus (means flesh) and relates to the word carnivores. And it is first derived from meat. A four-ounce portion of steak has almost 100mgs of carnitine. But the supplemental dose that most people take is about 2 to 3 grams and also depends upon the diet a person consumes. At the same time, our body can also be made this by itself.  It is a quaternary ammonium compound, also known as L-b-hydroxy-c-N-trimethyl aminobutyric acid.

The synthesis of this supplement takes place in a variety of organs. But the liver and kidneys seem to have the highest activity of carnitine synthesis. It acts as a transporter of long-chain fatty acid into the mitochondria. That can derive from our diet and can synthesize in the body. It synthesizes two essential amino acids in the body, lysine and methionine. But to produce it in a maximum amount, we need a large amount of vitamin C. 

Synthetic pathway

Here let’s take a look at how carnitine has been synthesized. This pathway is highly preserved as four critical enzymes have been utilized during this process. To begin the process of protein degradation. That results in the production of lysine residues, for example, trimethyl lysine. We can get it via the following reactions:

 Now, this L carnitine would act as a mediator of transporting long-chain fatty acyl chain into the mitochondria for beta-oxidation that results in their destruction if we have more carnitine in the body. That can shuttle more fatty acid into the mitochondria; then, they can burn more fat.

Different types of Carnitine

Acetyl L-carnitine:  This is often called ALCAR. This is possibly the effective form for your brain. Studies also suggest that it benefits people with neurodegenerative diseases.
D-carnitine: This inactive form of carnitine causes a deficiency in your body by inhibiting the absorption of other more useful forms of this element.
L-carnitine L-tartrate: This is commonly added to sports supplements due to its rapid absorption rate. It aids in muscle soreness and recovery from exercise.
Propionyl-L-carnitine: This form is well suited for circulatory issues such as peripheral vascular disease and high blood pressure. It boosts the production of nitric oxide, improving blood flow.

 

Carnitine - Healthcodes DNA™

Functions of Carnitine in the human body

Burns excess fats: One of the most widely used functions of carnitine is that it converts fats and glucose into energy by metabolizing them. It increases the oxidation of long-chain fatty acids that help manage human weight loss. It reduces the stored amount of fat present in your body. This results in the enhancement of exercise performance of individuals, directly linking to their weight loss.

L-carnitine not only reduces the fat stored deep inside the belly that is wrapped around the organs. Such as the liver and intestine, thus decreasing the chances of fatty liver disorders and other health problems. It is therefore understood that it could aid your body’s energy production by metabolizing the carbohydrates and long heavy chains of lipids, thus providing you with the best way to lose weight. Evidence shows that it burns calories by growing calorie expenses.

Helping in weight loss (Maintaining muscle integrity): Although L carnitine help in the burning of fat tissues inside the body to produce energy, what if that energy is still not used up? It will again restore the form of fat in our bodies. That is why 3 to 4 hours of exercise per week recommend with its intake. Supplementing with it can also play an essential role in restoring the damage caused by intensive training.

This is because L carnitine provides an alternative energy source through fat breakdown instead of muscle glycogen for energy production, preventing lactic acid production in muscles. Including it in our routine enhances our muscle mass, resulting in a decrease in physical and mental fatigue and a reduction in body weight. Supplementation of L-carnitine also positively influences the recovery process after exercise.

Improves insulin sensitivity and weight loss: Carnitine enhances insulin sensitivity in people with diabetes, and this is super important because insulin sensitivity is directly related to weight loss. A more insulin-sensitive body means our body doesn’t have to release Tons of insulin to process carbohydrates constantly. It will then start burning fats. 
Antioxidant effect: Carnitine also inhibits the oxidative damage of tissues. And act as a potent antioxidant (free radical scavenger). Studies show that oxidative stress influences the pathophysiology of many inherited neurometabolic disorders and the brain’s actions. As the center of their attention because of large oxygen consumption in the brain to provide energy. As it can easily cross the blood-brain barrier, L carnitine supplementation significantly prevents neurometabolic disorders. 
Carnitine as a memory booster: The supplements have been increasingly used to boost memory and brain functions. It is also seen to be very fruitful in age-related dementia. L-carnitine also helps to increase fertility in men. This also enhances the blood flow toward the muscles. Heart energy is also coming mainly from fats and L carnitine. It also acts to catalyze our immune system.

Dosing

The dosage of l-carnitine depends on the carnitine availability in your body and the body’s weight.

In adult males

It has been used only by adult males in portions of 2 grams per oral a day.

In infants

It has sometimes been used in oral doses of 50-100 mg/kg daily for up to 14 months. 

NOTE: Feel free to talk to your medical practitioner to search out what pill might be better for a particular illness.  

Supplements containing the fat burner Carnitine

Different supplements available are:

L carnitine 500 mg, L carnitine 1000 mg. 

Liquid L carnitine syrup and ALCAR 500 mg are also available that you can use to get it for the maintenance of your body weight; it is a lipotropic injection for weight loss: A significant weight loss in people has been seen who had taken this lipotropic injection.

 

Carnitine - Healthcodes DNA™

Safe use of Carnitine-containing supplements

If you try to lose weight, the recommended approved medical dose is 2grams or less carnitine per day. You must follow up with the doctor’s guidelines if you take other supplements for weight loss or dieting.

Natural sources that are rich in Carnitine you can use for fat control:

Different dairy products, including meat, fish, chicken, and pork, contain plenty of this. But their effect on the human body depends upon the appropriate way of using them and post-workout after their intake. The figure illustrates the approx. Amount of carnitine available in them:

Precautions

Pregnancy: You must reside in the cautious zone and prevent its use. Because there is no authentic evidence that supports the use of L carnitine during pregnancy.

During lactation: These particles had no unique lactation-related uses. Within the conventional ballpark of diet, removing levocarnitine into breast milk is relatively continuous. This supplement is safe when taken orally or intravenously while breastfeeding in the quantities prescribed by the medical practitioner. A small amount of it has now been given to babies in lactation and formula, providing no reported side effects. Mothers with carnitine dysfunction seem to naturally produce insufficient quantities of carnitine into their breast milk for their nursed children. Who might otherwise need levocarnitine replacement therapy? Preterm babies and children are very often defective in levocarnitine and entail intake. 

Side Effects

When given orally: It is likely peaceful when chosen to take for twelve weeks or as prescribed by the physician. Still, it could cause many side effects such as: 

Stomach problems like stomach acid production, Nausea, Vomiting, Diarrhea, and Hallucinations. It also could affect the feces, breath, and moisture from the air’s feces, breath, and humidity to provide a “fishy” stench. 

Try not to take D-carnitine and DL-carnitine. These kinds of carnitine might inhibit the effects of L-carnitine and produce diseases that depict L-carnitine deficit. Know L-carnitine diet interacts with certain antimicrobial drugs.  Anybody thinking about taking L-carnitine should consult their general practitioner to discuss any pills. They are taking inappropriate medication connections.

 

Carnitine - Healthcodes DNA™

Is L-carnitine good for weight loss in humans?

We are now familiar that L carnitine takes part in fat metabolism and aids in weight loss due to the complex nature of the human body. There is still a need for more research to confirm its use for weight loss. Let’s compare different meta-analyses. For example, comparing weight loss in women in an eight-week survey. The women who exercise four times a week lose their weight and found that there is no difference in losing weight between those who did take l carnitine and those who didn’t. At the same time, in a research study on obese people. Researchers have found that people taking it managed to lose about 2.9 pounds of weight more than those who did not.

Conclusion

Before taking Carnitine weight loss pills, do a DNA health test to ensure you will lose weight.

Your health, nutrition, and fitness can be improved by taking the HealthCodes DNA tests, which help you learn more about your unique genetic makeup. It will also help you eliminate medicines that don’t work for you, design a diet and exercise plan tailored to your needs, and select weight reduction products that work best for your body type.

With HealthCodes DNA’s genetic training programs, you’ll be able to determine the long-term impacts of your weight loss routines and learn how to use Carnitine weight loss pills in your overall plan for losing weight successfully.

After acquiring your kit, you’ll have your results in about three weeks. Customized macronutrients, dietary sensitivities or allergies, and an exercise regimen based on your genetics are included in the print and digital versions of the findings. These plans will assist in identifying the best way of living for you.

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  1. What information we collect
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Web Behavior Information. We and our third-party partners use cookies and similar technologies (such as web beacons, tags, scripts and device identifiers) to help us recognize you, customize and improve your experience, provide security, analyze usage of our Services (such as to analyze your interactions with the results, reports, and other features of the Service), gather demographic information about our user base, to offer our products and services to you, to monitor the success of marketing programs, and to serve targeted advertising on our site and on other sites around the Internet. We and our third-party partners do not use your sensitive information, such as Genetic Information and Self-Reported Information for targeted advertising. We may receive reports based on the use of these technologies by these companies on an individual as well as aggregated basis. Users can control the use of cookies at the individual browser level. If you reject cookies, you may still use our site, but your ability to use some features or areas of our site may be limited.

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  1. Other Types of Information.

We are always working to enhance our Services with new products, applications and features that may result in the collection of new and different types of information. We will update our privacy statement, as needed.

  1. How we use and share information

HealthCodes DNA will use and share your personal information with third-parties only in the ways that are described in this privacy statement.

  1. Using information to provide, analyze and improve our Services

We use the information described above in Section 3 to operate, provide, analyze and improve our Services. These activities may include, among other things, using your information in a manner consistent with other commitments in this privacy statement, to:

  1. open your account, enable purchases and process payments, communicate with you, and implement your requests (e.g., referrals);
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  • process and deliver your genetic testing results;
  • perform research & development activities, which may include, for example, conducting data analysis and research in order to develop new or improve existing products and services, and performing quality control activities.

You may be able to opt-in, opt-out or otherwise adjust your preferences of having your information used for certain of these activities. Please see below to learn more.

We use mobile analytics software to allow us to better understand the functionality of our Mobile Software on your phone. This software may record information such as how often you use the application, the events that occur within the application, aggregated usage, performance data, and where the application was downloaded from. We do not link the information we store within the analytics software to any personally identifiable information you submit within the mobile application.

  1. Using information with your consent

You have the choice to participate in HealthCodes DNA Research by providing your consent. “HealthCodes DNA Research” refers to research aimed at publication in peer-reviewed journals and other research funded by the federal government (such as the National Institutes of Health – NIH) conducted by HealthCodes DNA. HealthCodes DNA Research may be sponsored by, conducted on behalf of, or in collaboration with third-parties, such as non-profit foundations, academic institutions or pharmaceutical companies.  HealthCodes DNA Research may study a specific group or population, identify potential areas or targets for therapeutics development, conduct or support the development of drugs, diagnostics or devices to diagnose, predict or treat medical or other health conditions, work with public, private and/or non-profit entities on genetic research initiatives, or otherwise create, commercialize, and apply this new knowledge to improve health care. HealthCodes DNA Research uses your aggregate or individual-level Genetic Information and Self-Reported Information as specified in the Terms of Service.

Consent process for research. Your Genetic Information and Self-Reported Information may be used for HealthCodes DNA Research only if you have consented to this use by completing a Research Initiatives Consent Document. If you have completed a Research Initiatives Consent Document:

  1. Your aggregated, de-identified Genetic Information may be used for either philanthropic or commercial research purposes as set forth more fully the Research Initiatives Consent Document.
  2. When your Genetic Information and Self-Reported Informationis being used for research purposes, it will not be linked to your Registration Information.
  1. Withdrawing your Consent.You may withdraw your consent to participate in HealthCodes DNA Research Initiatives at any time by emailing us at support@healthcodesdna.com. HealthCodes DNA will not include your Genetic Information or Self-Reported Information in new research occurring after 30 days from the receipt of your request. Any research involving your data that has already been performed or published prior to our receipt of your request will not be reversed, undone, or withdrawn. If you withdraw your consent for research your Genetic Information and Self-Reported Information may still be used by us and shared with our third-party service providers to provide and improve our Services (as described in Section 4.a), and shared as Aggregate Information that does not identify you as an individual (as described in Section 4.d).
  2. What happens if you do NOT consent to HealthCodes DNA Research?If you do not complete a Research Initiatives Consent Document or any additional consent agreement with HealthCodes DNA, your information will not be used for HealthCodes DNA Research Initiatives and you will not be able to use HealthCodes DNA Services.
  1. Recruiting for external research

Academic institutions, healthcare organizations, and other groups are always conducting interesting new research projects. We want to make you aware of these opportunities. While we do not share individual-level Genetic Information or Self-Reported Information with third-parties without your consent, from time to time we may inform you of third-party research opportunities for which you may be eligible. For example, if a university tells us about a new cancer research project, we may send an email to HealthCodes DNA members who potentially fit the relevant eligibility criteria based on their Self-Reported Information to make them aware of the research project and provide a link to participate with the research organization conducting the study.

  1. Information we share with third-parties
  • General service providers.We share the information described above in Section 3 with our service providers, as necessary to provide their services to us. Service providers are third-parties (other companies or individuals) that help us to provide, analyze and improve our Services. For example, we work with third-party laboratories and contractors to process and analyze your saliva sample for purposes of generating your Genetic Information

NOTE: Our service providers act on HealthCodes DNA’s behalf. While we implement procedures and contractual terms to protect the confidentiality and security of your information, we cannot guarantee the confidentiality and security of your information due to the inherent risks associated with storing and transmitting data electronically.

When you purchase a testing kit and report from HealthCodes DNA, you are instructed to send a saliva sample to our third-party laboratory with a unique barcode label. The unique barcode identifies you to us but not to the laboratory. We may also be required to provide to the laboratory, your sex and date of birth or age pursuant to clinical laboratory requirements such as the Clinical Laboratory Improvement Amendments (CLIA). No other Registration Information such as your name, address, email, phone number or other contact information) is required or provided to the laboratory. The receiving personnel at the laboratory will remove and discard your “sender information” from the packaging (e.g., name, address) before testing personnel receive the samples for processing. Receiving personnel do not perform testing, and testing personnel handle saliva samples that are labeled only with the unique barcode. DNA and saliva samples are destroyed after the laboratory completes its work, provided that laboratory legal and regulatory requirements no longer require the actual samples to be maintained. A de-identified copy of genotyping data may be kept in accordance with CLIA. The laboratory securely sends the resulting Genetic Information to our third party reporting company along with your unique barcode. Genetic Information is stored securely on our servers; the laboratory also stores your Genetic Information, but again, labeled only with the barcode.

  • “Targeted advertising” service providers.We may permit third-party advertising networks and providers to collect Web Behavior Information on our Service to help us to deliver targeted online advertisements (“ads”) to you. They use cookies and similar technologies (such as JavaScript, beacons, device identifiers, location data, and clear gifs) to compile information about your browser’s or device’s visits and usage patterns on our Services and on other websites over time, which helps to better personalize ads to match your interests, and to measure the effectiveness of ad campaigns.

If you wish to not have this information used for the purpose of serving you targeted ads, you may be able to opt-out of many advertising networks by visiting here and here (if you are located in Canada, click here; or if you are located in the European Union click here). Please note this does not mean that you have opted-out of being served advertising. You will continue to receive generic ads.

  • Aggregate information.We may share aggregate information with third-parties, which is any information that has been stripped of your Registration (e.g., your name and contact information) and aggregated with information of others so that you cannot reasonably be identified as an individual (“Aggregate Information”). This Aggregate Information is different from “individual-level” information. Individual-level Genetic Information or Self-Reported Information of data about a single individual’s genotypes, diseases or other traits/characteristics information. For example, Aggregate Information may include a statement that “30% of our female users share a particular genetic trait,” without providing any data or testing results specific to any individual user. We may provide such Aggregate Information in commercial arrangements with our business partners. In contrast, individual-level Genetic Information could reveal whether a specific user has a particular genetic trait, or all of the Genetic Information about that user. HealthCodes DNA will ask for your consent to share individual-level Genetic Information or Self-Reported Information with any third-party, other than our service providers as necessary for us to provide the Services to you.
  • Information we share with commonly owned entities.We may share some or all of your information with other companies under common ownership or control of HealthCodes DNA, which may include our subsidiaries, our corporate parent, or any other subsidiaries owned by our corporate parent in order to provide you better service and improve user experience. We may provide additional notice and ask for your consent if we wish to share your information with our commonly owned entities in a materially different way than discussed in this Privacy Statement.
  1. Disclosures required by law

Under certain circumstances your information may be subject to disclosure pursuant to judicial or other government subpoenas, warrants, or orders, or in coordination with regulatory authorities, we may be required to disclose personal data in response to lawful requests by public authorities, including to meet national security or law enforcement requirements. HealthCodes DNA will preserve and disclose any and all information to law enforcement agencies or others if required to do so by law or in the good faith belief that such preservation or disclosure is reasonably necessary to: (a) comply with legal or regulatory process (such as a judicial proceeding, court order, or government inquiry) or obligations that HealthCodes DNA may owe pursuant to ethical and other professional rules, laws, and regulations; (b) enforce the HealthCodes DNA Terms of Service and other policies; (c) respond to claims that any content violates the rights of third-parties; or (d) protect the rights, property, or personal safety of HealthCodes DNA, its employees, its users, its clients, and the public.

NOTE: If you are participating in HealthCodes DNA Research, HealthCodes DNA will withhold disclosure of your personal information involved in such research in response to judicial or other government subpoenas, warrants or orders in accordance with any applicable Certificate of Confidentiality that HealthCodes DNA and/or any of its third party providers has obtained from the National Institutes of Health (NIH). There are limits to what the Certificate of Confidentiality covers so please visit the Certificates of Confidentiality Kiosk ( https://grants.nih.gov/grants/policy/coc/index.htm).

  1. Your choices
  2. Access to your account

If your Registration Information changes, you may access, correct or update most of it from your Account page. You may also modify and delete certain of your information. Please note that you may not be able to delete User Content that has been shared with others through the Service and that you may not be able to delete information that has been shared with third-parties, though we can work with you to prohibit your data from being shared with third-parties in the future. We will respond to your request to access within 30 days.

  1. Marketing communications

By registering for an account, you are agreeing that we may send you promotional emails about our Services. You can opt-out of such emails by clicking the “unsubscribe” button at the bottom of any of our or third-party promotional email communications. Please note that you may not opt-out of receiving non-promotional messages regarding your account, such as technical notices, purchase confirmations, or Service-related emails.

  1. Information you choose to share with others

You may decide to disclose your personal information to friends and/or family members, doctors or other health care professionals, and/or other individuals outside of our Services, including through third-party services such as social networks and third-party apps that connect to our website and mobile apps through our application programming interface (“API”). These third-parties may use your personal information differently than we do under this Privacy Statement. Please make such choices carefully and review the privacy policies of all other third-parties involved in the transaction. For example, if you have enabled a HealthCodes DNA sharing feature with another person who downloads a third-party app that uses our API, your information may also be obtained by that third-party app developer and, potentially, by other users of that third-party app.

In general, personal information, once shared or disclosed, can be difficult to contain or retrieve. HealthCodes DNA will have no responsibility or liability for any consequences that may result because you have released or shared personal information with others.

  1. Account closure

If you no longer wish to participate in our Services or no longer wish to have your personal information be used, you may close your account by sending a request to support@healthcodesdna.com. When closing an account, we remove all Genetic Information within your account (or profile) within thirty (30) days of our receipt of your request. As stated in any applicable Consent Document, however, Genetic Information and/or Self-Reported Information that you have previously provided and for which you have given consent to use in HealthCodes DNA Research cannot be removed from ongoing or completed studies that use the information. Our contracted genotyping laboratory may also retain your Genetic Information as required by local law and we may retain backup copies for a limited period of time pursuant to our data protection policies. In addition, we retain limited Registration Information related to your order history (e.g., name, contact, and transaction data) as long as your account is active or as needed to provide you services, as well as for accounting, audit and compliance purposes.

  1. Important Information
  2. Security measures

HealthCodes DNA takes seriously the trust you place in us. To prevent unauthorized access or disclosure, to maintain data accuracy, and to ensure the appropriate use of information, HealthCodes DNA uses a range of physical, technical, and administrative measures to safeguard your Personal Information. In particular, all connections to and from our website and mobile application are encrypted using Extended Validation Secure Socket Layer (EV SSL) technology.

Please recognize that protecting your Personal Information is also your responsibility. We ask you to be responsible for safeguarding your password, secret questions and answers, and other authentication information you use to access our Services. You should not disclose your authentication information to any third-party and should immediately notify HealthCodes DNA of any unauthorized use of your password. HealthCodes DNA cannot secure Personal Information that you release on your own or that you request us to release.

Your information collected through the Service may be stored and processed in the United States or any other country in which HealthCodes DNA or its subsidiaries, affiliates or service providers maintain facilities and, therefore, your information may be subject to the laws of those other jurisdictions which may be different from the laws of your country of residence.

  1. Business transactions

In the event that HealthCodes DNA goes through a business transition such as a merger, acquisition by another company, or sale of all or a portion of its assets, your information will likely be among the assets transferred. In such a case, your information would remain subject to the promises made in any pre-existing Privacy Statement.

  1. Linked websites

HealthCodes DNA provides links to third-party websites operated by organizations not affiliated with HealthCodes DNA. HealthCodes DNA does not disclose your information to organizations operating such linked third-party websites. HealthCodes DNA does not review or endorse, and is not responsible for, the privacy practices of these organizations. We encourage you to read the privacy statements of each and every website that you visit. This Privacy Statement applies solely to information collected by HealthCodes DNA.

  1. Children’s privacy

HealthCodes DNA is committed to protecting the privacy of children as well as adults. Neither HealthCodes DNA nor any of its Services are designed for, intended to attract, or directed toward children under the age of 18. A parent or guardian, however, may collect a saliva sample from, create an account for, and provide information related to, his or her child. The parent or guardian assumes full responsibility for ensuring that the information that he/she provides to HealthCodes DNA about his or her child is kept secure and that the information submitted is accurate.

  1. Changes to this Privacy Statement

Whenever this Privacy Statement is changed in a material way, a notice will be posted as part of this Privacy Statement and on our customers’ account login pages for 30 days. After 30 days the changes will become effective. In addition, all customers will receive an email with notification of the changes prior to the change becoming effective.

  1. Contact Information

If you have questions about this Privacy Statement, please email HealthCodes DNA at info@HealthCodesDNA.com.